Study shows that activity in the subthalamic nucleus reflects action outcomes and consequent adaptation in humans; this can be modified through bursts of electrical stimulation, with potential to restore healthy brain function in people with neurological disorders like Parkinson’s disease.
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In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002140
Article Title: Dynamic modulation of subthalamic nucleus activity facilitates adaptive behavior
Author Countries: United Kingdom, Germany
Funding: DMH is supported by a postdoctoral grant from the Independent Research Fund Denmark (0168-00014B). AP, HT and PB are supported by the Medical Research Council (MC_UU_00003/2). RB is supported by the Medical Research Council (MC_UU_00003/1). This research was funded by the UKRI [MC_UU_00003/2]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Journal
PLoS Biology
DOI
10.1371/journal.pbio.3002140
COI Statement
Competing interests: The authors have declared that no competing interests exist.
